The five-year initiative New Skills for Youth (NSFY) aimed to transform career readiness education and bridge the skills gap by supporting innovative strategies in 10 states across the United States. This Advance CTE report shares the successes and challenges of sustaining the work beyond the conclusion of the NSFY initiative, and through a global pandemic, in six of the states: Kentucky, Louisiana, Massachusetts, Ohio, Rhode Island, and Wisconsin. From the experiences of each of these states, the resource presents specific recommendations and action steps for state and local leaders on how to sustain career pathways for long-term success.