The National Governors Association launched the Strengthening Substance Use Disorder (SUD) Systems of Care (SUD Learning Collaborative) in June 2020. The purpose of the SUD Learning Collaborative was to improve coordination across the continuum of prevention, treatment, and recovery services for individuals affected by SUD and opioid use disorder. From June 2020 through March 2021, Governor-appointed teams from six states — Kentucky, New York, Oregon, Virginia, West Virginia, and Wyoming — engaged in strategic planning analysis, with the goal of addressing their state’s respective linkage to SUD care and treatment priorities. This report helps states address challenges related to these focus areas.